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| Calponin interacts with actin, tropomyosin, and calmodulin. It is restrict expressed in smooth muscle cells and is involved in the regulation of smooth muscle contraction. Anti-calponin has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma. |
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