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S-100

The S-100 is expressed in benign nevi and malignant melanoma cells. Nearly all benign melanocytic lesions contain S-100 protein which is also observed in over 95% of malignant melanomas.

 

The antibody reacts with α and β subunits of S-100. Positive results aid in the differential diagnosis of melanomas and nerve sheath tumors from carcinomas. For this purpose, the S-100 antibody is a sensitive marker, but it is not as specific as other antibodies. Therefore, it is recommended that S-100 antibody be used in a panel containing antibodies to keratin, HMB45, and epithelial membrane antigen. The S-100 antibody cannot distinguish between benign and malignant lesions.

 

Image Cat No. Description Use Config Spec Price Order
60-0061 61-0061 Rb x S100 Stained melanoma 10x small.jpg 60-0061 Rabbit anti-S100, Ready-To-Use, 6 mL IVD RTU $130.00
 
Cat. 60-0061 small pic.jpg 61-0061 Rabbit anti S-100, Concentrate, 1 mL IVD Concentrate $200.00