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Von Willebrand Factor (Factor VIII RA)
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| vWF, as known as Factor VIII related antigen (Factor VIII RA), is a sensitive marker of benign blood vessels and has been used for the study of angiogenesis in neoplasm such as breast cancer. vWF is seldom expressed in poorly differentiated vascular tumors. Therefore, anti-vWF antibody must be used in conjunction with other more sensitive markers of endothelial cells (e.g. CD34 and CD31) when identifying angiosarcomas. There is overlap between the expression of von Willebrand factor in vascular and lymphatic endothelium. |
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